Natalia T. Freund

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

Jon M. Steichen, Daniel W. Kulp, Talar Tokatlian et al. · Immunity · 2016 · 429 citations · Full text

Germline Precursors, Immunology, Immunodominance +17

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice

Amelia Escolano, Jon M. Steichen, Pia Dosenovic et al. · Cell · 2016 · 337 citations · Full text

Autoimmune Disease, Human Retrovirus, Immunology +6

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

Pia Dosenovic, Lotta von Boehmer, Amelia Escolano et al. · Cell · 2015 · 274 citations · Full text

Primary Immunodeficiency, Human Retrovirus, Immunology +6

Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo

Max Medina-Ramírez, Fernando Garcés, Amelia Escolano et al. · The Journal of Experimental Medicine · 2017 · 193 citations · Full text

Virus Structure, Crystal Structure, Human Retrovirus +15

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice

Andrew T. McGuire, Matthew D. Gray, Pia Dosenovic et al. · Nature Communications · 2016 · 190 citations · Full text