Sam C. Nalle

Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis

Liping Su, Le Shen, Daniel Clayburgh et al. · Gastroenterology · 2008 · 430 citations · Full text

Inflammation, Chronic Inflammatory Diseases, Mucosal Immunology +9

TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis

Liping Su, Sam C. Nalle, Le Shen et al. · Gastroenterology · 2013 · 382 citations · Full text

Inflammation, Signal Transduction, Immunology +10

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

Christopher R. Weber, Sam C. Nalle, Maria Tretiakova et al. · Laboratory Investigation · 2008 · 359 citations · Full text

Inflammation, Autoimmune Disease, Early Neoplastic Transformation +9

Molecular correlates differentiate response to atezolizumab (atezo) + bevacizumab (bev) vs sunitinib (sun): Results from a phase III study (IMmotion151) in untreated metastatic renal cell carcinoma (mRCC)

Brian I. Rini, Mahrukh Huseni, Michael B. Atkins et al. · Annals of Oncology · 2018 · 72 citations

Urology, Genitourinary Cancer, Medicine +9

Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability

Sam C. Nalle, Li Zuo, Ma. Lora Drizella M. Ong et al. · Journal of Clinical Investigation · 2019 · 63 citations · Full text

Immunology, Gastroenterology, Pathology +17