Kristine A. Keon

Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response

David Sharon, Séverine Cathelin, Sara Mirali et al. · Science Translational Medicine · 2019 · 193 citations

Mitochondrial Translation Overcomes, Cellular Physiology, Oxidative Stress +17

Toosendanin, a novel potent vacuolar-type H⁺-translocating ATPase inhibitor, sensitizes cancer cells to chemotherapy by blocking protective autophagy

Yu Dong, Guo‐Yuan Zhu, Sheng-Fang Wang et al. · International Journal of Biological Sciences · 2022 · 38 citations · Full text

Coordinated conformational changes in the V1 complex during V-ATPase reversible dissociation

Thamiya Vasanthakumar, Kristine A. Keon, Stephanie A. Bueler et al. · Nature Structural & Molecular Biology · 2022 · 31 citations

Biophysical Modeling, Biochemistry, Protein Assembly +11

CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7

Yong Zi Tan, Y.M. Abbas, Jing Wu et al. · Life Science Alliance · 2022 · 29 citations · Full text

Rotary Catalysis, Molecular Biology, Cellular Physiology +16

Structure of V-ATPase from citrus fruit

Yong Zi Tan, Kristine A. Keon, Rana Abdelaziz et al. · Structure · 2022 · 17 citations

Citrus Fruit, Biochemistry, Enzyme Catalysis +2