Helena Mertlíková‐Kaiserová

Flavonoids as protectors against doxorubicin cardiotoxicity: Role of iron chelation, antioxidant activity and inhibition of carbonyl reductase

Helena Mertlíková‐Kaiserová, Tomáš Šimůnek, W. J. F. van der Vijgh et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2007 · 131 citations · Full text

Doxorubicin Cardiotoxicity, Iron Chelation, Biochemistry +8

Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4-Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology

Ivana Mejdrová, Dominika Chalupská, Pavla Plačková et al. · Journal of Medicinal Chemistry · 2016 · 65 citations · Full text

Viral Replication, Viral Polymerase Structure, Molecular Biology +19

Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action

Ivana Mejdrová, Dominika Chalupská, Martin Kögler et al. · Journal of Medicinal Chemistry · 2015 · 64 citations · Full text

Viral Replication, Viral Polymerase Structure, Viral Polymerase Mechanism +22

In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity

Michaela Adamcová, Tomáš Šimůnek, Helena Mertlíková‐Kaiserová et al. · Toxicology · 2007 · 62 citations

Cardiac Muscle, Cardiomyopathy, Biochemical Markers +9

Protectors against doxorubicin-induced cardiotoxicity: Flavonoids

Aalt Bast, Helena Mertlíková‐Kaiserová, Gertjan J.M. den Hartog et al. · Cell Biology and Toxicology · 2006 · 62 citations

Doxorubicin-induced Cardiotoxicity, Medicinal Chemistry, Pharmacology +6