Derek LeRoith

Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice

Klara Sjögren, Jun‐Li Liu, K. Blad et al. · Proceedings of the National Academy of Sciences · 1999 · 952 citations · Full text

Insulin Signaling, Embryology, Metabolic Syndrome +19

Circulating levels of IGF-1 directly regulate bone growth and density

Shoshana Yakar, Clifford J. Rosen, Wesley G. Beamer et al. · Journal of Clinical Investigation · 2002 · 841 citations · Full text

Human Growth, Bone Growth, Cell Growth +17

Circulating levels of IGF-1 directly regulate bone growth and density

Shoshana Yakar, Clifford J. Rosen, Wesley G. Beamer et al. · Journal of Clinical Investigation · 2002 · 717 citations

Bone Growth, Cell Growth, Igf Molecule +16

Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: Direct correlation with clinical retinopathy of prematurity

Ann Hellström, Carole Perruzzi, Meihua Ju et al. · Proceedings of the National Academy of Sciences · 2001 · 578 citations · Full text

Serum insulin-like growth factor I regulates brain amyloid-β levels

Eva Carro, José Luís Trejo, Teresa Gómez‐Isla et al. · Nature Medicine · 2002 · 448 citations

Neurodegenerative Diseases, Molecular Neuroscience, Protein Misfolding +7