Attilio V. Vargiu

Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations

Attilio V. Vargiu, Hiroshi Nikaido · Proceedings of the National Academy of Sciences · 2012 · 224 citations · Full text

Engineering, Acrb Efflux Pump, Flexible Binding Site +17

Chirality Effects on Peptide Self-Assembly Unraveled from Molecules to Materials

Ana M. García, Daniel Iglesias, Evelina Parisi et al. · Chem · 2018 · 207 citations · Full text

Supramolecular Assembly, Engineering, Protein Folding +8

Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

Hanno Sjuts, Attilio V. Vargiu, Steven M. Kwasny et al. · Proceedings of the National Academy of Sciences · 2016 · 204 citations · Full text

AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity

Jessica M. A. Blair, Vassiliy N. Bavro, Vito Ricci et al. · Proceedings of the National Academy of Sciences · 2015 · 183 citations · Full text

Drug Target, Molecular Biology, Pharmacotherapy +22

Molecular Mechanism of MBX2319 Inhibition of Escherichia coli AcrB Multidrug Efflux Pump and Comparison with Other Inhibitors

Attilio V. Vargiu, Paolo Ruggerone, Timothy J. Opperman et al. · Antimicrobial Agents and Chemotherapy · 2014 · 165 citations · Full text

Bacteriology, Antimicrobial Chemotherapy, Computer Docking +25