Targeted Degradation of Oncogenic KRAS ^G12C by VHL-Recruiting PROTACs

Michael J. Bond, Ling Chu, Dhanusha A. Nalawansha, +2

ACS Central Science

Synthesis of α‐Aryl Nitriles through Palladium‐Catalyzed Decarboxylative Coupling of Cyanoacetate Salts with Aryl Halides and Triflates

Rui Shang, Dongsheng Ji, Ling Chu, +2

Angewandte Chemie International Edition

Pd-Catalyzed Enantioselective C–H Iodination: Asymmetric Synthesis of Chiral Diarylmethylamines

Ling Chu, Xiaochen Wang, Curtis E. Moore, +2

Journal of the American Chemical Society

EngineeringAsymmetric SynthesisOrganic ChemistryOrganometallic CatalysisCatalysis +9

Ligand-enabled cross-coupling of C(sp3)–H bonds with arylboron reagents via Pd(II)/Pd(0) catalysis

Kelvin S. L. Chan, Masayuki Wasa, Ling Chu, +3

Nature Chemistry

Cross-coupling ReactionEngineeringLigand-enabled Cross-couplingOrganometallic CatalysisCatalysis +4

Room-temperature enantioselective C–H iodination via kinetic resolution

Ling Chu, Kai-Jiong Xiao, Jin‐Quan Yu

Science

Cross-coupling ReactionNovel OrganocatalystsEngineeringKinetic ResolutionOrganic Chemistry +11

Remote <i>Meta</i>-C–H Activation Using a Pyridine-Based Template: Achieving Site-Selectivity via the Recognition of Distance and Geometry

Ling Chu, Minghui Shang, Keita Tanaka, +4

ACS Central Science

Achieving Site-selectivityEngineeringAlkene MetathesisNatural SciencesDiversity-oriented Synthesis +12

Enantioselective C−H Olefination of α‐Hydroxy and α‐Amino Phenylacetic Acids by Kinetic Resolution

Kai‐Jiong Xiao, Ling Chu, Jin‐Quan Yu

Angewandte Chemie International Edition

Palladium-Catalyzed Decarboxylative Coupling of Potassium Nitrophenyl Acetates with Aryl Halides

Rui Shang, Zheng Huang, Ling Chu, +2

Organic Letters

Potassium NitrophenylChemical EngineeringCross-coupling ReactionAryl ChloridesEngineering +9

Ligand‐Promoted <i>ortho</i>‐CH Amination with Pd Catalysts

Dajian Zhu, Guoqiang Yang, Jian He, +6

Angewandte Chemie International Edition

SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing

Yanfei Hou, Zhimeng Wang, Peiyuan Liu, +8

Immunity

Signal TransductionBiochemistryNatural SciencesLxr-mediated Lipid MetabolismMolecular Biology +5