Prostaglandin E synthase

Makoto Murakami, Toshihiro Tanioka, I Kudo

Prostaglandins & Other Lipid Mediators

IL-13 and IL-4 inhibit bone resorption by suppressing cyclooxygenase-2-dependent prostaglandin synthesis in osteoblasts

Yoshiko Onoe, Chisato Miyaura, T Kaminakayashiki, +8

The Journal of Immunology

Molecular nature of phospholipases A2 involved in prostaglandin I2 synthesis in human umbilical vein endothelial cells. Possible participation of cytosolic and extracellular type II phospholipases A2.

Makoto Murakami, I Kudo, Keiichi Inoue

Journal of Biological Chemistry

ImmunologyInflammationMolecular PharmacologyThrombosisAngiogenesis +21

A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa

T C Moon, Makoto Murakami, I Kudo, +4

Inflammation Research

Bioorganic ChemistryBiochemistryAntiparasitic AgentMedicineNatural Sciences +7

Triggering of degranulation in mast cells by exogenous type II phospholipase A2.

Makoto Murakami, Naomi Hara, I Kudo, +1

The Journal of Immunology

Mast Cell DisorderImmunologyCell DeathCellular PhysiologyInflammation +16

Mouse bone marrow-derived mast cells undergo exocytosis, prostanoid generation, and cytokine expression in response to G protein-activating polybasic compounds after coculture with fibroblasts in the presence of c-kit ligand

Tohru Ogasawara, Makoto Murakami, T Suzuki-Nishimura, +2

The Journal of Immunology

Possible role of mammalian secretory group II phospholipase A2 in T-lymphocyte activation: implication in propagation of inflammatory reaction.

Yoshinori Asaoka, Ken‐ichi Yoshida, Yukio Sasaki, +4

Proceedings of the National Academy of Sciences

Inflammatory ReactionImmunologyCell DeathImmunologic MechanismLipid Movement +19

Site-specific mutagenesis on cloned DNAs: generation of a mutant of Escherichia coli tyrosine suppressor tRNA in which the sequence G-T-T-C corresponding to the universal G-T-pseudouracil-C sequence of tRNAs is changed to G-A-T-C.

I Kudo, Michael Leineweber, Uttam L. RajBhandary

Proceedings of the National Academy of Sciences

EngineeringSite-specific MutagenesisGeneticsMolecular BiologyMolecular Genetics +17

Dual regulation of cytosolic phospholipase A2 in mast cells after cross-linking of FC epsilon-receptor.

Yoshihito Nakatani, Makoto Murakami, I Kudo, +1

The Journal of Immunology

Mast Cell DisorderImmunologyDual RegulationCellular PhysiologyInflammation +16

Cyclooxygenase-2-dependent delayed prostaglandin D2 generation is initiated by nerve growth factor in rat peritoneal mast cells: its augmentation by extracellular type II secretory phospholipase A2

Makoto Murakami, Kinji Tada, Koichi Nakajima, +1

The Journal of Immunology