Hironao Takasawa

The in vivo-in vitro replecative DNA synthesis (RDS) test with hepatocytes prepared from male B6C3F1 mice as an early prediction assay for putative nongenotoxic (Ames-negative) mouse hepatocarcinogens

Makoto Miyawaga, Hironao Takasawa, Akio Sugiyama et al. · Mutation Research/Genetic Toxicology · 1995 · 88 citations

Pharmacy, Molecular Biology, Toxicology +17

JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results

Yoshifumi Uno, Hajime Kojima, Takashi Omori et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2015 · 86 citations

Pharmacy, Toxicology, Molecular Toxicology +11

Evaluation of the repeated-dose liver and gastrointestinal tract micronucleus assays with 22 chemicals using young adult rats: Summary of the collaborative study by the Collaborative Study Group for the Micronucleus Test (CSGMT)/The Japanese Environmental Mutagen Society (JEMS) – Mammalian Mutagenicity Study Group (MMS)

Shuichi Hamada, Wakako Ohyama, Rie Takashima et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2015 · 82 citations · Full text

Pharmacy, Toxicology, Environmental Toxicology +16

An in vivo-in vitro replicative DNA synthesis (RDS) test using rat hepatocytes as an early prediction assay for nongenotoxic hepatocarcinogens screening of 22 known positives and 25 noncarcinogens

Yoshifumi Uno, Hironao Takasawa, Makoto Miyagawa et al. · Mutation Research/Genetic Toxicology · 1994 · 72 citations

Pharmacy, Molecular Biology, Toxicology +17

Evaluation of a liver micronucleus assay with 12 chemicals using young rats (II): a study by the Collaborative Study Group for the Micronucleus Test/Japanese Environmental Mutagen Society-Mammalian Mutagenicity Study Group

Hiroshi Suzuki, Hironao Takasawa, Kazuo Kobayashi et al. · Mutagenesis · 2008 · 65 citations

Pharmacy, Toxicology, Developmental Toxicology +10