Frederike Schmidt

Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling

Philipp Arnold, I. Boll, Michelle Rothaug et al. · Scientific Reports · 2017 · 56 citations · Full text

Metalloprotease meprin β is activated by transmembrane serine protease matriptase-2 at the cell surface thereby enhancing APP shedding

Felix Jäckle, Frederike Schmidt, Rielana Wichert et al. · Biochemical Journal · 2015 · 38 citations

Protein Secretion, Protein Function, Signal Transduction +15

Ectodomain shedding of CD99 within highly conserved regions is mediated by the metalloprotease meprin β and promotes transendothelial cell migration

Tillmann Bedau, Florian Peters, Johannes Prox et al. · The FASEB Journal · 2016 · 35 citations

Calcium negatively regulates meprin β activity and attenuates substrate cleavage

Philipp Arnold, Frederike Schmidt, Johannes Prox et al. · The FASEB Journal · 2015 · 18 citations

Protein Secretion, Molecular Regulation, Cellular Physiology +20

Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration <i>in vitro</i>

Tillmann Bedau, Neele Schumacher, Florian Peters et al. · Oncotarget · 2017 · 15 citations · Full text