Concepedia

Frankie S. Mak

FS

4

Publications

125

Citations

4

H-Index

2012

Active since

Affiliations

GlaxoSmithKline (China)(Current)

Institute of Medicinal Plant Development

Frankie S. Mak is an author at GlaxoSmithKline (China) specializing in pharmacology, medicine, and biochemistry.

Top concepts

MedicineBiochemistryPharmacologyDrug DiscoveryMolecular PharmacologyPharmacotherapyNeuropharmacologyMolecular ModelingBiomolecular EngineeringEngineering

Publications per year

2012–2014

4

Publications

4

Synthesis and Pharmacological Evaluation of Dual Acting Ligands Targeting the Adenosine A<sub>2A</sub> and Dopamine D<sub>2</sub> Receptors for the Potential Treatment of Parkinson’s Disease

Manuela Jörg, Lauren T. May, Frankie S. Mak et al. · Journal of Medicinal Chemistry · 2014 · 51 citations · Full text

Dual Acting Molecules, Drug Target, Pharmacotherapy +18

Investigation of novel ropinirole analogues: synthesis, pharmacological evaluation and computational analysis of dopamine D<sub>2</sub> receptor functionalized congeners and homobivalent ligands

Manuela Jörg, Agnieszka A. Kaczor, Frankie S. Mak et al. · MedChemComm · 2014 · 32 citations

Engineering, Computational Analysis, Pharmacotherapy +17

Novel adenosine A2A receptor ligands: A synthetic, functional and computational investigation of selected literature adenosine A2A receptor antagonists for extending into extracellular space

Manuela Jörg, Jeremy Shonberg, Frankie S. Mak et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 28 citations · Full text

Signal Transduction, Biochemistry, G Protein-coupled Receptor +8

Synthesis, molecular structure, NMR spectroscopic and computational analysis of a selective adenosine A2A antagonist, ZM 241385

Manuela Jörg, Mark Agostino, Elizabeth Yuriev et al. · Structural Chemistry · 2012 · 14 citations

Molecular Pharmacology, Biochemistry, Functional Selectivity +6

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