A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

Christopher B. Newgard, Jie An, James R. Bain, +17

Cell Metabolism

Insulin ResistanceObesityMetabolic SyndromeMetabolic DisorderBiochemistry +10

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase

Phillip J. White, Robert W. McGarrah, Paul A. Grimsrud, +18

Cell Metabolism

Phosphatase Integrate BcaaSignal TransductionLipid MetabolismBiochemistryAtp-citrate Lyase +7

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

Christopher B. Newgard, Jie An, James R. Bain, +17

Cell Metabolism

Insulin ResistanceObesityMetabolic SyndromeMetabolic DisorderBiochemistry +10

Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1

Cong Guo, Anton E. Ludvik, Michelle Arlotto, +9

Nature Communications

Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors

Jeffery S. Tessem, Larry G. Moss, Lily C. Chao, +7

Proceedings of the National Academy of Sciences

The STEDMAN Project: Biophysical, Biochemical and Metabolic Effects of a Behavioral Weight Loss Intervention during Weight Loss, Maintenance, and Regain

Lillian F. Lien, Andrea M. Haqq, Michelle Arlotto, +14

OMICS A Journal of Integrative Biology

NutritionPhysical ActivityMetabolic DisorderWeight ManagementComprehensive Metabolic Profiling +19

The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design

Andrea M. Haqq, Lillian F. Lien, Jarol Boan, +12

Contemporary Clinical Trials

ObesityNutritionPhysiologyObesity ManagementWeight Management +5

Creation of versatile cloning platforms for transgene expression and dCas9-based epigenome editing

Jonathan M. Haldeman, Amanda E. Conway, Michelle Arlotto, +4

Nucleic Acids Research

Modular PlatformTransgene ExpressionGeneticsEpigenetic ChangeMolecular Biology +19

The Pediatric Obesity Microbiome and Metabolism Study (POMMS): Methods, Baseline Data, and Early Insights

Jessica R. McCann, Nathan A. Bihlmeyer, Kimberly Roche, +22

Obesity

HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis

Ashot Sargsyan, Ludivine Doridot, Sarah Anissa Hannou, +12

JCI Insight

ImmunologyMetabolic RemodelingHuman HgfacChrebp-regulated HepatokineSystemic Fuel Homeostasis +22