Hidenori Homma

Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation

Meihua Jin, Hiroki Shiwaku, Hikari Tanaka et al. · Nature Communications · 2021 · 210 citations · Full text

HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer’s disease

Kyota Fujita, Kazumi Motoki, Kazuhiko Tagawa et al. · Scientific Reports · 2016 · 149 citations · Full text

YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology

Hikari Tanaka, Hidenori Homma, Kyota Fujita et al. · Nature Communications · 2020 · 110 citations · Full text

Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain

Kazuhiko Tagawa, Hidenori Homma, Ayumu Saito et al. · Human Molecular Genetics · 2014 · 87 citations · Full text

<scp>HMGB</scp> 1 facilitates repair of mitochondrial <scp>DNA</scp> damage and extends the lifespan of mutant ataxin‐1 knock‐in mice

Hikaru Ito, Kyota Fujita, Kazuhiko Tagawa et al. · EMBO Molecular Medicine · 2014 · 82 citations · Full text