Sharon L. Guffy

Evolution of a highly active and enantiospecific metalloenzyme from short peptides

Sabine Studer, Douglas A. Hansen, Zbigniew Pianowski et al. · Science · 2018 · 173 citations

An excited state underlies gene regulation of a transcriptional riboswitch

Bo Zhao, Sharon L. Guffy, Benfeard Williams et al. · Nature Chemical Biology · 2017 · 129 citations · Full text

Transcriptional Regulation, Natural Sciences, Rna Structure Prediction +8

Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1

Vikram Khipple Mulligan, Sean D. Workman, Tianjun Sun et al. · Proceedings of the National Academy of Sciences · 2021 · 74 citations · Full text

Targeted Mutagenesis of the Multicopy Myrosinase Gene Family in Allotetraploid Brassica juncea Reduces Pungency in Fresh Leaves across Environments

Dale Karlson, Julius P. Mojica, Thomas J. Poorten et al. · Plants · 2022 · 31 citations · Full text

Protocols for Requirement-Driven Protein Design in the Rosetta Modeling Program

Sharon L. Guffy, Frank D. Teets, Minnie I. Langlois et al. · Journal of Chemical Information and Modeling · 2018 · 22 citations