Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

Robin Kate Kelley, Makoto Ueno, Changhoon Yoo, +208

The Lancet

UrologySurgical OncologyGastrointestinal OncologyMedicineBiliary Cancer +3

Interleukin–10 Controls Neutrophilic Infiltration, Hepatocyte Proliferation, and Liver Fibrosis Induced by Carbon Tetrachloride in Mice

Hubert Louis, Jean‐Luc Van Laethem, Wei Wu, +8

Hepatology

Short course chemotherapy followed by concomitant chemoradiotherapy and surgery in locally advanced rectal cancer: a randomized multicentric phase II study

Raphaël Maréchal, Bertrand Vos, Marc Polus, +10

Annals of Oncology

Surgical OncologyRadiation TherapyGastrointestinal OncologyMedicineAdvanced Rectal Cancer +6

CD4+ T cells play an important role in acute experimental pancreatitis in mice

Anne Demols, Olivier Le Moine, Fabrice Desalle, +3

Gastroenterology

InflammationImportant RoleAcute Experimental PancreatitisT-regulatory CellImmune Regulation +8

Gemcitabine and oxaliplatin (GEMOX) in gemcitabine refractory advanced pancreatic adenocarcinoma: a phase II study

Anne Demols, Marc Peeters, Marc Polus, +5

British Journal of Cancer

Surgical OncologyPancreatic CancerGastrointestinal OncologyGem TherapyMedicine +12

Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitis

Anne Demols, Jean‐Luc Van Laethem, Eric Quertinmont, +4

American Journal of Physiology-Gastrointestinal and Liver Physiology

Cold liver ischemia-reperfusion injury critically depends on liver T cells and is improved by donor pretreatment with interleukin 10 in mice

Olivier Le Moine, Hubert Louis, Anne Demols, +5

Hepatology

Regorafenib after failure of gemcitabine and platinum-based chemotherapy for locally advanced/metastatic biliary tumors: REACHIN, a randomized, double-blind, phase II trial

Anne Demols, Ivan Borbath, Marc Van den Eynde, +9

Annals of Oncology

Phase Ii TrialMedicineBiliary CancerPathologyAdvanced/metastatic Biliary Tumors +4

N-Acetylcysteine Decreases Severity of Acute Pancreatitis in Mice

Anne Demols, Jean‐Luc Van Laethem, Eric Quertinmont, +4

Pancreas

Combination of gemcitabine and cetuximab in patients with advanced cholangiocarcinoma: a phase II study of the Belgian Group of Digestive Oncology

Ivan Borbath, Antonino Ceratti, Chris Verslype, +9

Annals of Oncology

HepatologyGastrointestinal OncologyMedicineBiliary CancerGastroenterology +7