Deletion of the Ca²+-activated potassium (BK) α-subunit but not the BKβ1-subunit leads to progressive hearing loss

Lukas Rüttiger, Matthias Sausbier, Ulrike Zimmermann, +16

Proceedings of the National Academy of Sciences

Thyroid Hormone Deficiency Before the Onset of Hearing Causes Irreversible Damage to Peripheral and Central Auditory Systems

Marlies Knipper, Christoph Zinn, H. Maier, +4

Journal of Neurophysiology

The Reduced Cochlear Output and the Failure to Adapt the Central Auditory Response Causes Tinnitus in Noise Exposed Rats

Lukas Rüttiger, Wibke Singer, Rama Panford-Walsh, +8

PLoS ONE

Ihcs Ribbon LossTinnitus PrevalenceNoiseTinnitus AnimalsAuditory Science +19

Lack of Bdnf and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss

Thomas Schimmang, Justin Tan, Marcus Müller, +6

Development

NeurotologyNeurotransmissionCellular NeurobiologyOuter Hair CellsAuditory Science +24

Noise-Induced Inner Hair Cell Ribbon Loss Disturbs Central Arc Mobilization: A Novel Molecular Paradigm for Understanding Tinnitus

Wibke Singer, Annalisa Zuccotti, Mirko Jaumann, +14

Molecular Neurobiology

Vestibular SystemNeurophysiologyNeuroanatomyTinnitusNovel Molecular Paradigm +9

Thyroid hormone affects Schwann cell and oligodendrocyte gene expression at the glial transition zone of the VIIIth nerve prior to cochlea function

Marlies Knipper, Christine E. Bandtlow, Lika Gestwa, +5

Development

Thyroid hormone is a critical determinant for the regulation of the cochlear motor protein prestin

Thomas Weber, Ulrike Zimmermann, Harald Winter, +5

Proceedings of the National Academy of Sciences

Signal TransductionPrestin GeneHormonal ReceptorGeneticsPhysiology +11

Tinnitus behavior and hearing function correlate with the reciprocal expression patterns of BDNF and Arg3.1/arc in auditory neurons following acoustic trauma

Justin Tan, Lukas Rüttiger, Rama Panford-Walsh, +8

Neuroscience

Reciprocal Expression PatternsHealth SciencesNeurophysiologyNeuroanatomyTinnitus +11

Two classes of outer hair cells along the tonotopic axis of the cochlea

Jutta Engel, Claudia Braig, Lukas Rüttiger, +10

Neuroscience

BiologyDevelopmental BiologyHealth SciencesNeuroanatomyTonotopic Axis +10

cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function

Mirko Jaumann, Juliane Dettling, Martin Gubelt, +20

Nature Medicine

Hair CellsMolecular PhysiologySignal TransductionCgmp-prkg1 SignalingPde5 Inhibition Shelter +9