Laurence Arnold - Concepedia

Author

Laurence Arnold

The Francis Crick Institute ORCID

Also Known As

Laurence Arnold, Laurence H. Arnold

Publications

350

Citations

H-Index

Concepts

All Affiliations

The Francis Crick Institute Pelago Bioscience (Sweden)

About

Laurence Arnold is an author at The Francis Crick Institute specializing in natural sciences, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	288
2	Natural Sciences	5	5	288
3	Biochemistry	4	4	266
4	Cell Biology	2	2	109
5	Chemical Biology	1	1	47

Laurence Arnold

Publications

345

Citations

H-Index

Page 1

	Year	Citations
Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction Laurence Arnold, Harriet C. T. Groom, Simone Kunzelmann, PLoS Pathogens Molecular RegulationMolecular BiologySamhd1 ActivityCd4+ T-cellsHuman Retrovirus	2015	110
The Interface between Catalytic and Hemopexin Domains in Matrix Metalloproteinase-1 Conceals a Collagen Binding Exosite Laurence Arnold, Louise E. Butt, Stephen H. Prior, Journal of Biological Chemistry Matrix Metalloproteinase-1 ConcealsProtein AssemblyMolecular BiologyCollagen BindingPeptide Science	2011	55
Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches Patrick J. McIntyre, P.M. Collins, Lukáš Vrzal, ACS Chemical Biology Molecular BiologyTumor BiologyMitotic Kinase Aurora-aReceptor Tyrosine KinaseMolecular Recognition	2017	54
A Continuous Enzyme-Coupled Assay for Triphosphohydrolase Activity of HIV-1 Restriction Factor SAMHD1 Laurence Arnold, Simone Kunzelmann, Martin R. Webb, Antimicrobial Agents and Chemotherapy Continuous Enzyme-coupled AssayAntiviral DrugChemical BiologyTriphosphohydrolase ActivityMedicinal Chemistry	2014	47
Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis E.R. Morris, Sarah J. Caswell, Simone Kunzelmann, Nature Communications	2020	45
CETSA MS Profiling for a Comparative Assessment of FDA-Approved Antivirals Repurposed for COVID-19 Therapy Identifies TRIP13 as a Remdesivir Off-Target Tomas Friman, Alexey Chernobrovkin, Daniel Martinez Molina, SLAS DISCOVERY Drug TargetImmunologyAntiviral DrugCetsa Ms ProfilingCovid-19	2020	22
High throughput screening of 0.5 million compounds against CRAF using Alpha CETSAⓇ Hannah Rowlands, Kirsten Tschapalda, Carolyn Blackett, SLAS DISCOVERY	2023	12

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