Ouabain, a steroid hormone that signals with slow calcium oscillations

Oleg Aizman, Per Uhlén, Mark Lal, +2

Proceedings of the National Academy of Sciences

Cardiac MuscleDigoxin AnalogSlow Calcium OscillationsCellular PhysiologyOxidative Stress +17

Cell Signaling Microdomain with Na,K-ATPase and Inositol 1,4,5-Trisphosphate Receptor Generates Calcium Oscillations

Ayako Miyakawa-Naito, Per Uhlén, Mark Lal, +5

Journal of Biological Chemistry

Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling

Mark Lal, Xuewen Song, Jennifer L. Pluznick, +7

Human Molecular Genetics

Role of oxidative stress in advanced glycation end product-induced mesangial cell activation

Mark Lal, Hjalmar Brismar, Ann‐Christine Eklöf, +1

Kidney International

Reductive StressBiochemistryLipid PeroxidationGlycobiologyRedox Biology +7

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

Bing He, Ping Chen, Sonia Zambrano, +18

Nature Communications

Combined antioxidant and COMT inhibitor treatment reverses renal abnormalities in diabetic rats.

Mark Lal, Anna Körner, Yosuke Matsuo, +6

Diabetes

Comt Inhibitor TreatmentRenal PathologyRenal InflammationGlucose HomeostasisK-atpase Activity +18

Na,K-ATPase signal transduction triggers CREB activation and dendritic growth

Luc Desfrère, Marie Karlsson, Hiromi Hiyoshi, +8

Proceedings of the National Academy of Sciences

Sodium PumpCellular NeurobiologySynaptic SignalingCellular PhysiologySocial Sciences +14

Molecular insights into the early stage of glomerular injury in IgA nephropathy using single-cell RNA sequencing

Sonia Zambrano, Liqun He, Toshiki Kano, +6

Kidney International

Glomerular DiseaseImmunologyGlomerulonephritisSingle Cell SequencingIga Glomerulonephritis +14

Retinoic acid receptor responder1 promotes development of glomerular diseases via the Nuclear Factor-κB signaling pathway

Katja Möller‐Hackbarth, Dina Dabaghie, Emmanuelle Charrin, +6

Kidney International

Glomerular DiseaseGlomerular DiseasesEndothelial CellsImmunologyRenal Inflammation +26

Rhophilin-1 Is a Key Regulator of the Podocyte Cytoskeleton and Is Essential for Glomerular Filtration

Mark Lal, Ann-Charlotte Andersson, Kan Katayama, +5

Journal of the American Society of Nephrology