R. Löser

In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells.

Katja Wosikowski, Elfi Biedermann, Benno Rattel et al. · PubMed · 2003 · 115 citations

Cell Cycle, Metronomic Chemotherapy, Immunotherapy +17

Polyethylene Glycol Conjugates of Methotrexate Varying in Their Molecular Weight from MW 750 to MW 40000:  Synthesis, Characterization, and Structure−Activity Relationships in Vitro and in Vivo

Katja Riebeseel, Elfi Biedermann, R. Löser et al. · Bioconjugate Chemistry · 2002 · 93 citations

Ethylene Glycol, Pharmaceutical Science, Engineering +16

WK175, a novel antitumor agent, decreases the intracellular nicotinamide adenine dinucleotide concentration and induces the apoptotic cascade in human leukemia cells.

Katja Wosikowski, Karin Mattern, Isabel Schemainda et al. · PubMed · 2002 · 89 citations

Novel Antitumor Agents, Medicine, Apoptosis +13

Inhibition of cholesterol synthesis in vitro by extracts and isolated compounds prepared from garlic and wild garlic

A. Sendl, M. Schliack, R. Löser et al. · Atherosclerosis · 1992 · 85 citations

Wild Garlic, Biosynthesis, Oxysterol +7

Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma.

Joachim Drevs, R. Löser, Benno Rattel et al. · PubMed · 2004 · 65 citations

Chemoprevention Strategy, Pathology, Metronomic Chemotherapy +18