Stephen Goodbourn

The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the <i>IFN</i> -β promoter

J. Andrejeva, Kay Childs, D. F. Young et al. · Proceedings of the National Academy of Sciences · 2004 · 971 citations · Full text

The V Protein of Simian Virus 5 Inhibits Interferon Signalling by Targeting STAT1 for Proteasome-Mediated Degradation

L. Didcock, D. F. Young, Stephen Goodbourn et al. · Journal of Virology · 1999 · 419 citations · Full text

Viral Replication, V Protein, Simian Virus 5 +16

The human β-interferon gene enhancer is under negative control

Stephen Goodbourn, Hal Burstein, Tom Maniatis · Cell · 1986 · 393 citations

Immunogenetics, Transcriptional Regulation, Genetics +6

Double-stranded RNA activates binding of NF-kappa B to an inducible element in the human beta-interferon promoter.

Kanna V. Visvanathan, Stephen Goodbourn · The EMBO Journal · 1989 · 313 citations · Full text

Transcriptional Regulation, Human Beta-interferon Promoter, Genetics +9

mda-5, but not RIG-I, is a common target for paramyxovirus V proteins

Kay Childs, Nicola Stock, Craig S. Ross et al. · Virology · 2006 · 299 citations

Paramyxovirus V Proteins, Molecular Virology, Pathogenesis +8