David J. Simpson

Loss of pRb expression in pituitary adenomas is associated with methylation of the RB1 CpG island.

David J. Simpson, Nigel A. Hibberts, Richard N. Clayton et al. · PubMed · 2000 · 214 citations

Medicine, Genetics, Molecular Genetics +17

CpG-island fragments from the HNRPA2B1/CBX3genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells

Steven G. Williams, Tracey Mustoe, Tony Mulcahy et al. · BMC Biotechnology · 2005 · 150 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Analysis of cyclin D1 (CCND1) allelic imbalance and overexpression in sporadic human pituitary tumors.

Nigel A. Hibberts, David J. Simpson, John Bicknell et al. · PubMed · 1999 · 124 citations

Medicine, Genetics, Molecular Genetics +17

Hypermethylation of the p16/CDKN2A/MTSI gene and loss of protein expression is associated with nonfunctional pituitary adenomas but not somatotrophinomas.

David J. Simpson, John Bicknell, Richard N. Clayton et al. · PubMed · 1999 · 111 citations

Medicine, Endocrinology, Genetics +17

Loss of expression of the growth inhibitory gene GADD45γ, in human pituitary adenomas, is associated with CpG island methylation

Adil Bahar, John Bicknell, David J. Simpson et al. · Oncogene · 2003 · 98 citations

Medicine, Endocrinology, Genetics +16