Intramolecular Nonbonded S···O Interaction Recognized in (Acylimino)thiadiazoline Derivatives as Angiotensin II Receptor Antagonists and Related Compounds

Yoshimitsu Nagao, Terukage Hirata, Satoru Goto, +4

Journal of the American Chemical Society

PharmacotherapyChemistryHeterocycle ChemistryRelated CompoundsPharmaceutical Chemistry +17

Highly Stereoselective Asymmetric Pummerer Reactions That Incorporate Intermolecular and Intramolecular Nonbonded S···O Interactions

Yoshimitsu Nagao, Satoshi Miyamoto, Motoyuki Miyamoto, +6

Journal of the American Chemical Society

Asymmetric total synthesis of ISP-I (myriocin, thermozymocidin), a potent immunosuppressive principle in the isaria sinclairii metabolite

Shigeki Sano, Yoshimaro Kobayashi, Tatsuya Kondo, +4

Tetrahedron Letters

BiosynthesisBioorganic ChemistryAsymmetric Total SynthesisBiochemistryPotent Immunosuppressive Principle +7

Pim-2 kinase is an important target of treatment for tumor progression and bone loss in myeloma

Masahiro Hiasa, Jumpei Teramachi, A Oda, +18

Leukemia

Hematological MalignancyBone LossBone Morphogenic ProteinMedicinePim-2 Kinase +8

Highly Enantioselective Catalytic Thiolysis of Prochiral Cyclic Dicarboxylic Anhydrides Utilizing a Bifunctional Chiral Sulfonamide

Takashi Honjo, Shigeki Sano, Motoo Shiro, +1

Angewandte Chemie International Edition

Chemical EngineeringEngineeringCatalytic DesymmetrizationOrganic ChemistryRelated Chiral Sulfonamides +10

Synthesis and reactivities of 3-Indocyanine-green-acyl-1,3-thiazolidine-2-thione (ICG-ATT) as a new near-infrared fluorescent-labeling reagent

Terukage Hirata, Hiromi Kogiso, Kenji Morimoto, +6

Bioorganic & Medicinal Chemistry

EngineeringOrganic ChemistryClick ChemistryChemistryHeterocycle Chemistry +2

Synthesis of New Quinolone Antibiotics Utilizing Azetidine Derivatives Obtained from 1-Azabicyclo[1.1.0]butane

Yoshifumi Ikee, Kana Hashimoto, Mai Kamino, +5

Chemical and Pharmaceutical Bulletin

Medicinal ChemistryDerivative (Chemistry)HeterocyclicBiochemistry3-Sulfenylazetidine Derivatives +10

Synthesis and antibacterial activities of new quinolone derivatives utilizing 1-azabicyclo[1.1.0]butane

Yoshifumi Ikee, Kana Hashimoto, Masaaki Nakashima, +4

Bioorganic & Medicinal Chemistry Letters

HeterocyclicOrganic ChemistryAntimicrobial ChemotherapyAntimicrobial CompoundNew Quinolone Derivatives +1

New Reaction Mode of the Horner-Wadsworth-Emmons Reaction for the Preparation of α-Fluoro-α,β-unsaturated Esters

Shigeki Sano, Tsuyoshi Ando, Kenji Yokoyama, +1

Synlett

Excellent E-selectivityHwe ReactionsEthyl 2-Fluoro-2-diethylphosphonoacetate 1EngineeringAlkene Metathesis +10

Toward (Z)-selective Horner–Wadsworth–Emmons reaction of aldehydes with 2-fluoro-2-diethylphosphonoacetic acid

Shigeki Sano, Rie Teranishi, Yoshimitsu Nagao

Tetrahedron Letters

Organic ChemistryFluorous Synthesis2-Fluoro-2-diethylphosphonoacetic AcidChemistry