Urolithin A suppresses RANKL-induced osteoclastogenesis and postmenopausal osteoporosis by, suppresses inflammation and downstream NF-κB activated pyroptosis pathways

Huaqiang Tao, Wenming Li, Wei Zhang, +13

Pharmacological Research

InflammationBone DiseaseUrologyDownstream Nf-κbMedicine +9

Punicalagin ameliorates collagen-induced arthritis by downregulating M1 macrophage and pyroptosis via NF-κB signaling pathway

Gaoran Ge, Jiaxiang Bai, Qing Wang, +10

Science China Life Sciences

InflammationRheumatologyAnti-inflammatoryInflammatory DiseaseAutoimmune Disease +10

ROS signaling cascades: dual regulations for osteoclast and osteoblast

Huaqiang Tao, Gaoran Ge, Xiaolong Liang, +4

Acta Biochimica et Biophysica Sinica

InflammationSclerostinSignal TransductionBiochemistryNitric Oxide +12

Biomimetic osteogenic peptide with mussel adhesion and osteoimmunomodulatory functions to ameliorate interfacial osseointegration under chronic inflammation

Jiaxiang Bai, Huaiyu Wang, Hao Chen, +9

Biomaterials

MechanobiologyInflammationSclerostinEngineeringBone Morphogenic Protein +12

Exosomes derived from miR-155-5p–overexpressing synovial mesenchymal stem cells prevent osteoarthritis via enhancing proliferation and migration, attenuating apoptosis, and modulating extracellular matrix secretion in chondrocytes

Zhirong Wang, Kai Yan, Gaoran Ge, +9

Cell Biology and Toxicology

Regenerative MedicineDevelopmental BiologyMedicineCartilage DegenerationOsteoarthritis +10

Regulating Macrophage Polarization in High Glucose Microenvironment Using Lithium‐Modified Bioglass‐Hydrogel for Diabetic Bone Regeneration

Zerui Wu, Jiaxiang Bai, Gaoran Ge, +11

Advanced Healthcare Materials

Tissue EngineeringEngineeringBiomaterials DesignDiabetic Bone RegenerationBiofabrication +18

TET2 regulates osteoclastogenesis by modulating autophagy in OVX-induced bone loss

Yang Chen, Huaqiang Tao, Haifeng Zhang, +12

Autophagy

Human bone mesenchymal stem cells-derived exosomal miRNA-361-5p alleviates osteoarthritis by downregulating DDX20 and inactivating the NF-κB signaling pathway

Yunxia Tao, Jing Zhou, Zhen Wang, +8

Bioorganic Chemistry

InflammationRheumatologyNf-κb Signaling PathwayMedicineImmunology +9

Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis

Xiaobin Guo, Jiaxiang Bai, Gaoran Ge, +11

Journal of Colloid and Interface Science

MechanobiologyTissue EngineeringEngineeringBioinspired Peptide AdhesionCell Adhesion +9

Engineering Stem Cell Recruitment and Osteoinduction via Bioadhesive Molecular Mimics to Improve Osteoporotic Bone-Implant Integration

Jiaxiang Bai, Gaoran Ge, Qing Wang, +6

Research