Hyungwoo Moon

Discovery of novel imidazole chemotypes as isoform-selective JNK3 inhibitors for the treatment of Alzheimer's disease

Joonhong Jun, Songyi Yang, Jung-Hun Lee et al. · European Journal of Medicinal Chemistry · 2022 · 26 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Isoform-selective Jnk3 Inhibitors +10

Discovery of 3-alkyl-5-aryl-1-pyrimidyl-1<i>H-</i>pyrazole derivatives as a novel selective inhibitor scaffold of JNK3

Youri Oh, Miyoung Jang, Hyunwook Cho et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2019 · 19 citations · Full text

Discovery of a Potent and Selective JNK3 Inhibitor with Neuroprotective Effect Against Amyloid β-Induced Neurotoxicity in Primary Rat Neurons

Joonhong Jun, Jihyun Baek, Songyi Yang et al. · International Journal of Molecular Sciences · 2021 · 17 citations · Full text

Primary Rat Neurons, Cell Death, Chemical Biology +20

Carbamate JNK3 Inhibitors Show Promise as Effective Treatments for Alzheimer’s Disease: In Vivo Studies on Mouse Models

Joonhong Jun, Hyungwoo Moon, Songyi Yang et al. · Journal of Medicinal Chemistry · 2023 · 17 citations · Full text

Novel 1,4,5,6-tetrahydrocyclopenta[d]imidazole-5-carboxamide-based JNK3 inhibitors: Design, synthesis, molecular docking, and therapeutic potential in neurodegenerative diseases

Joonhong Jun, Jihyun Baek, Dahyun Kang et al. · European Journal of Medicinal Chemistry · 2022 · 15 citations · Full text

Neurodegenerative Diseases, Medicinal Chemistry, Therapeutic Potential +12