Simon Fietz

Comprehensive analysis of tumor necrosis factor receptor TNFRSF9 (4-1BB) DNA methylation with regard to molecular and clinicopathological features, immune infiltrates, and response prediction to immunotherapy in melanoma

Anne Fröhlich, Sophia Loick, Emma Bawden et al. · EBioMedicine · 2020 · 71 citations · Full text

Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma

Anne Fröhlich, Judith Sirokay, Simon Fietz et al. · EBioMedicine · 2020 · 65 citations · Full text

CTLA4 promoter methylation predicts response and progression-free survival in stage IV melanoma treated with anti-CTLA-4 immunotherapy (ipilimumab)

Simon Fietz, Romina Zarbl, Dennis Niebel et al. · Cancer Immunology Immunotherapy · 2020 · 32 citations · Full text

Talimogene laherparepvec treatment to overcome loco-regional acquired resistance to immune checkpoint blockade in tumor stage IIIB–IV M1c melanoma patients

Anne Fröhlich, Dennis Niebel, Simon Fietz et al. · Cancer Immunology Immunotherapy · 2020 · 29 citations · Full text

DNA methylation regulates TIGIT expression within the melanoma microenvironment, is prognostic for overall survival, and predicts progression-free survival in patients treated with anti-PD-1 immunotherapy

Dennis Niebel, Anne Fröhlich, Romina Zarbl et al. · Clinical Epigenetics · 2022 · 26 citations · Full text