SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

Emma S. Winkler, Adam L. Bailey, Natasha M. Kafai, +14

Nature Immunology

Inflammatory Lung DiseaseLung InflammationSars-cov-2 InfectionViral PathogenesisImmunology +6

A complement–microglial axis drives synapse loss during virus-induced memory impairment

Michael J. Vasek, Charise Garber, Denise Dorsey, +19

Nature

Complement SystemMedicineImmunologyBrain-immune InteractionNeuroscience +5

Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection

Emma S. Winkler, Pavlo Gilchuk, Jinsheng Yu, +17

Cell

VaccinationVaccine TargetImmunologyHumoral ImmunityAntibody Engineering +6

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

Yong Zhang, Dailing Mao, William T. Roswit, +16

Nature Immunology

Host ResponseChromatinMedicineViral ImmunityImmunology +8

MicroRNA-138 suppresses invasion and promotes apoptosis in head and neck squamous cell carcinoma cell lines

Xiqiang Liu, Lu Jiang, Anxun Wang, +3

Cancer Letters

Tumor BiologyOncologyMedicinePathologyCell Death +9

Tumor–Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer

Daoxiang Zhang, Lin Li, Hongmei Jiang, +7

Cancer Research

MicroRNA-222 regulates cell invasion by targeting matrix metalloproteinase 1 (MMP1) and manganese superoxide dismutase 2 (SOD2) in tongue squamous cell carcinoma cell lines.

Xiqiang Liu, Jinsheng Yu, Lu Jiang, +4

PubMed

MedicineMicrorna DeregulationCancer Cell BiologyPathologyMmp1 Expression +12

MicroRNA Profiling and Head and Neck Cancer

Xiqiang Liu, Zugen Chen, Jinsheng Yu, +2

Comparative and Functional Genomics

Microrna ProfilingOncologyMicrorna ExpressionMedicinePathology +13

Gene expression profiles in febrile children with defined viral and bacterial infection

Xinran Hu, Jinsheng Yu, Seth D. Crosby, +1

Proceedings of the National Academy of Sciences

Viral DiagnosticsViral PathogenesisImmunologyGene Expression ProfilesMedical Microbiology +17

Proteomic Signatures of Heart Failure in Relation to Left Ventricular Ejection Fraction

Luigi Adamo, Jinsheng Yu, Cibele Rocha‐Resende, +3

Journal of the American College of Cardiology

CardiomyopathyHeart FailureCardiovascular DiseaseMedicinePhysiology +6