Kimitaka Miyamoto

Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase

Takashi Mano, Rodney W. Stevens, Kazuo Ando et al. · Bioorganic & Medicinal Chemistry · 2003 · 57 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

4-[5-Fluoro-3-[4-(2-methyl-1<i>H</i>-imidazol-1-yl)benzyloxy]phenyl]-3,4,5,6- tetrahydro-2<i>H</i>-pyran-4-carboxamide, an Orally Active Inhibitor of 5-Lipoxygenase with Improved Pharmacokinetic and Toxicology Characteristics

Takashi Mano, Yoshiyuki Okumura, Minoru Sakakibara et al. · Journal of Medicinal Chemistry · 2003 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Optimization of Imidazole 5-Lipoxygenase Inhibitors and Selection and Synthesis of a Development Candidate

Takashi Mano, Rodney W. Stevens, Kazuo Ando et al. · Chemical and Pharmaceutical Bulletin · 2005 · 22 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17