A Transgenic Drosophila Model Demonstrates That the Helicobacter pylori CagA Protein Functions as a Eukaryotic Gab Adaptor

Crystal M. Botham, Anica M. Wandler, Karen Guillemin

PLoS Pathogens

GeneticsPathologyMolecular GeneticsEukaryotic Gab AdaptorSignaling Pathway +16

Dynamic Evolution of the LPS-Detoxifying Enzyme Intestinal Alkaline Phosphatase in Zebrafish and Other Vertebrates

Ye Yang, Anica M. Wandler, John H. Postlethwait, +1

Frontiers in Immunology

Dynamic EvolutionRedox BiologyBone Morphogenic ProteinBioenergeticsMetabolism +17

Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes

Lauren K. Meyer, Benjamin J. Huang, Cristina Delgado-Martín, +11

Journal of Clinical Investigation

Lymphocyte DevelopmentT-regulatory CellImmunologyImmunotherapyHematological Malignancy +14

The bacterial virulence factor CagA induces microbial dysbiosis that contributes to excessive epithelial cell proliferation in the Drosophila gut

Tiffani A. Jones, Diane Z. Hernandez, Zoë C. Wong, +2

PLoS Pathogens

DysbiosisHost-microbe InteractionsGut MicrobiotaTransgenic Drosophila ModelMicrobial Dysbiosis +18

Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia

Anica M. Wandler, Benjamin J. Huang, Jeffrey W. Craig, +20

Leukemia

Hematological MalignancyVivo Dexamethasone ResistanceAutoimmune DiseaseMalignant Blood DisorderImmunology +6

Transgenic Expression of the Helicobacter pylori Virulence Factor CagA Promotes Apoptosis or Tumorigenesis through JNK Activation in Drosophila

Anica M. Wandler, Karen Guillemin

PLoS Pathogens

Cell DeathJnk-dependent MannerCancer BiologyTumor BiologySignaling Pathway +16

Rapid deployment of SARS-CoV-2 testing: The CLIAHUB

Emily Crawford, Irene Acosta, Vida Ahyong, +181

PLoS Pathogens

Viral DiagnosticsJeremy BancroftCovid-19 PandemicClinical EpidemiologyVirus Transmission +6

Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy

Olga Ksionda, Marsilius Mues, Anica M. Wandler, +8

PLoS ONE

Pi3k InhibitorsMixed-phenotype Acute LeukemiaImmunologyCancer BiologyTumor Biology +18

Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila

David W. Reid, Jonathan B. Muyskens, James T. Neal, +5

Frontiers in Cellular and Infection Microbiology

Signal TransductionMolecular PhysiologyDevelopmental BiologySignaling PathwayDevelopmental Genetics +13

High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality Predictions

Marsilius Mues, Laila Karra, Damià Romero–Moya, +8

Cell Reports