Nigel J. O’Neil

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Hong Xu, Marco Di Antonio, Steven McKinney et al. · Nature Communications · 2017 · 573 citations · Full text

Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

Matthieu Le Gallo, Andrea O’Hara, Meghan L. Rudd et al. · Nature Genetics · 2012 · 429 citations · Full text

Chromatin, Somatic Variant, Somatic Mutations +11

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human

Daniele Bergamaschi, Yardena Samuels, Nigel J. O’Neil et al. · Nature Genetics · 2003 · 373 citations

Apoptosis, Immunology, Cell Death +7

RTEL1 Maintains Genomic Stability by Suppressing Homologous Recombination

Louise J. Barber, Jillian L. Youds, Jordan D. Ward et al. · Cell · 2008 · 359 citations · Full text

Genome Instability, Homologous Recombination, Genetics +4

RTEL-1 Enforces Meiotic Crossover Interference and Homeostasis

Jillian L. Youds, David G. Mets, Michael J. McIlwraith et al. · Science · 2010 · 177 citations · Full text