Exome Capture Reveals ZNF423 and CEP164 Mutations, Linking Renal Ciliopathies to DNA Damage Response Signaling

Moumita Chaki, Rannar Airik, Amiya K. Ghosh, +69

Cell

Genome InstabilityLinking Renal CiliopathiesCep164 MutationsGeneticsGenomic Mechanism +4

Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation

Leandro Z. Agudelo, Duarte M. S. Ferreira, Igor Červenka, +17

Cell Metabolism

ObesityMetabolic SyndromeInflammationEnergy MetabolismMolecular Physiology +10

Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance

Leandro Z. Agudelo, Duarte M. S. Ferreira, Shamim Dadvar, +11

Nature Communications

Mitogen-Activated Protein Kinases Promote WNT/β-Catenin Signaling via Phosphorylation of LRP6

Igor Červenka, Joshua H. Wolf, J. Mašek, +6

Molecular and Cellular Biology

Sequential Activation and Inactivation of Dishevelled in the Wnt/β-Catenin Pathway by Casein Kinases

Ondřej Bernatík, Ranjani Sri Ganji, Jacomijn P. Dijksterhuis, +6

Journal of Biological Chemistry

Molecular RegulationMolecular BiologyWnt/β-catenin PathwayCellular PhysiologySignaling Pathway +18

CXXC5 Is a Novel BMP4-regulated Modulator of Wnt Signaling in Neural Stem Cells

Therése Andersson, Erik Södersten, Joshua K. Duckworth, +6

Journal of Biological Chemistry

Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes

Vicente Martínez-Redondo, Paulo R. Jannig, Jorge C. Correia, +11

Journal of Biological Chemistry

Transcriptional RegulationGeneticsRna SplicingGene RegulationTarget Genes +6

Multivalent insulin receptor activation using insulin–DNA origami nanostructures

Joel Spratt, José M. Dias, Christina Kolonelou, +12

Nature Nanotechnology

Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins

Igor Červenka, Jana Valnohová, Ondřej Bernatík, +13

Proceedings of the National Academy of Sciences

Molecular BiologyCytoskeletonWnt SignalingCell CycleCellular Physiology +16

Functional Analysis of Dishevelled-3 Phosphorylation Identifies Distinct Mechanisms Driven by Casein Kinase 1ϵ and Frizzled5

Ondřej Bernatík, Kateřina Šedová, Carolin Schille, +6

Journal of Biological Chemistry