Michael R. Pears

High Resolution 1H NMR-based Metabolomics Indicates a Neurotransmitter Cycling Deficit in Cerebral Tissue from a Mouse Model of Batten Disease

Michael R. Pears, Jonathan D. Cooper, Hannah M. Mitchison et al. · Journal of Biological Chemistry · 2005 · 147 citations · Full text

Batten Disease, Neurochemical Biomarkers, Glutamate Metabolism +17

Polynucleotide Phosphorylase Activity May Be Modulated by Metabolites in Escherichia coli

Salima Nurmohamed, Helen A. Vincent, Christopher M. Titman et al. · Journal of Biological Chemistry · 2011 · 61 citations · Full text

Pnpase Deletion, Molecular Biology, Escherichia Coli +18

Metabolomic investigation of CLN6 neuronal ceroid lipofuscinosis in affected South Hampshire sheep

Michael R. Pears, Reza M. Salek, David N. Palmer et al. · Journal of Neuroscience Research · 2007 · 24 citations · Full text

Caprine, Brain Development, Gross Brain Atrophy +31

Deletion of <i>btn</i> 1, an orthologue of <i>CLN</i> 3, increases glycolysis and perturbs amino acidmetabolism in the fission yeast model of Batten disease

Michael R. Pears, Sandra Codlin, Rebecca L. Haines et al. · Molecular BioSystems · 2010 · 21 citations

A metabolomic comparison of mouse models of the Neuronal Ceroid Lipofuscinoses

Reza M. Salek, Michael R. Pears, Jonathan D. Cooper et al. · Journal of Biomolecular NMR · 2011 · 11 citations · Full text

Neuronal Ceroid Lipofuscinoses, Neuro-oncology, Lipid Analysis +11