Long-term protective efficacy with a BCG-prime ID93/GLA-SE boost regimen against the hyper-virulent Mycobacterium tuberculosis strain K in a mouse model

Kee Woong Kwon, Ara Lee, Sasha E. Larsen, +6

Scientific Reports

Mycobacterium tuberculosis GrpE, A Heat-Shock Stress Responsive Chaperone, Promotes Th1-Biased T Cell Immune Response via TLR4-Mediated Activation of Dendritic Cells

Woo Sik Kim, In Duk Jung, Jong Seok Kim, +4

Frontiers in Cellular and Infection Microbiology

Antigen-Specific IFN-γ/IL-17-Co-Producing CD4+ T-Cells are the Determinants for Protective Efficacy of Tuberculosis Subunit Vaccine

Han‐Gyu Choi, Kee Woong Kwon, Seunga Choi, +6

Vaccines

<i>Mycobacterium tuberculosis</i> Rv3628 drives Th1-type T cell immunity via TLR2-mediated activation of dendritic cells and displays vaccine potential against the hyper-virulent Beijing K strain

Woo Sik Kim, Jong-Seok Kim, Seung Bin, +8

Oncotarget

Tuberculosis VaccineAdaptive Immune SystemInnate Immune SystemImmunologyImmune Regulation +20

Viral coinfection promotes tuberculosis immunopathogenesis by type I IFN signaling-dependent impediment of Th1 cell pulmonary influx

Tae Gun Kang, Kee Woong Kwon, Kyung Soo Kim, +4

Nature Communications

An Alternative Dendritic Cell-Induced Murine Model of Asthma Exhibiting a Robust Th2/Th17-Skewed Response

Sang Chul Park, Hongmin Kim, Yeeun Bak, +5

Allergy Asthma and Immunology Research

PPE39 of the <i>Mycobacterium tuberculosis</i> strain Beijing/K induces Th1-cell polarization through dendritic cell maturation

Hong-Hee Choi, Kee Woong Kwon, Seung Jung Han, +5

Journal of Cell Science

Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis

Woo Sik Kim, Jong-Seok Kim, Seung Bin, +7

PLoS ONE

Inflammatory Lung DiseaseLung InflammationAdaptive Immune SystemInnate Immune SystemImmunology +17

A Novel Therapeutic Approach Using Mesenchymal Stem Cells to Protect Against <i>Mycobacterium abscessus</i>

Jong-Seok Kim, Sang-Ho Cha, Woo Sik Kim, +11

Stem Cells

Cell TherapyMicrobial PathogensLung InflammationInnate Immune SystemImmunology +26

Pulmonary immunity and durable protection induced by the ID93/GLA-SE vaccine candidate against the hyper-virulent Korean Beijing Mycobacterium tuberculosis strain K

Seung Bin, Woo Sik Kim, Jong-Seok Kim, +7

Vaccine

VaccinationPulmonary TuberculosisVaccine DevelopmentVaccine TargetTuberculosis Prevention +8