Philippe C Després

Perturbing proteomes at single residue resolution using base editing

Philippe C Després, Alexandre K. Dubé, M. Seki et al. · Nature Communications · 2020 · 68 citations · Full text

Protein context shapes the specificity of SH3 domain-mediated interactions in vivo

Ugo Dionne, Émilie Bourgault, Alexandre K. Dubé et al. · Nature Communications · 2021 · 63 citations · Full text

<i>beditor</i> : A Computational Workflow for Designing Libraries of Guide RNAs for CRISPR-Mediated Base Editing

Rohan Dandage, Philippe C Després, Nozomu Yachie et al. · Genetics · 2019 · 43 citations · Full text

Asymmetrical dose responses shape the evolutionary trade-off between antifungal resistance and nutrient use

Philippe C Després, Angel F. Cisneros, Emilie M. M. Alexander et al. · Nature Ecology & Evolution · 2022 · 37 citations

Biology, Disease Resistance, Asymmetrical Dose Responses +9

Epistasis between promoter activity and coding mutations shapes gene evolvability

Angel F. Cisneros, Isabelle Gagnon‐Arsenault, Alexandre K. Dubé et al. · Science Advances · 2023 · 32 citations · Full text

High Promoter Activity, Promoter Activity, Medicine +14