The Ca2+ Sensor Stromal Interaction Molecule 1 (STIM1) Is Necessary and Sufficient for the Store-Operated Ca2+ Entry Function of Transient Receptor Potential Canonical (TRPC) 1 and 4 Channels in Endothelial Cells

Premanand Sundivakkam, Marc Freichel, Vandana Singh, +5

Molecular Pharmacology

The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation

Chinnaswamy Tiruppathì, Dheeraj Soni, Dongmei Wang, +13

Nature Immunology

InflammationTranscriptional RegulationMedicineImmunologyGene Expression +9

Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen

Jose A. Martinez, Masaki Kobayashi, Anand Krishnan, +5

Experimental Neurology

Regenerative MedicineRegenerationNeuroregenerationDevelopmental BiologyPeripheral Nerve Injury +8

Evidence for Epigenetic Regulation of Gene Expression and Function in Chronic Experimental Diabetic Neuropathy

Chu Cheng, Masaki Kobayashi, Jose A. Martinez, +6

Journal of Neuropathology & Experimental Neurology

Epigenetic ChangeGeneticsDiabetic PolyneuropathyEpigeneticsMirna Profiles +16

PEG-mediated one-pot multicomponent reactions for the efficient synthesis of functionalized dihydropyridines and their functional group dependent DNA cleavage activity

Suman Kalyan Pal, Vandana Singh, Prolay Das, +1

Bioorganic Chemistry

Combinatorial ChemistryBioorganic ChemistryBiochemistryNatural SciencesMolecular Biology +4

Antiarthritic Potential of Calotropis procera Leaf Fractions in FCA-Induced Arthritic Rats: Involvement of Cellular Inflammatory Mediators and Other Biomarkers

Vandana Singh, Shashikant C. Dhawale, Faiyaz Shakeel, +2

Agriculture

ImmunologyPathologyFca-induced Arthritic RatsInflammatory ArthritisOxidative Stress +19

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

Ikenna Obi, Matilda Rentoft, Vandana Singh, +5

Nucleic Acids Research

GeneticsDna AnalysisMolecular BiologyMolecular GeneticsCell Cycle +16

Enzyme-free optical DNA mapping of the human genome using competitive binding

Vilhelm Müller, Albertas Dvirnas, John Andersson, +6

Nucleic Acids Research

GeneticsDna AnalysisMolecular BiologyGenomicsHuman Genome +18

Ca²⁺ influx via TRPC channels induces NF-κB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells

Prabhakar B. Thippegowda, Vandana Singh, Premanand Sundivakkam, +3

American Journal of Physiology-Cell Physiology

Quantifying DNA damage induced by ionizing radiation and hyperthermia using single DNA molecule imaging

Vandana Singh, Pegah Johansson, Dmitry Torchinsky, +5

Translational Oncology

Dna DamageEngineeringRadiation EffectRadiation ExposureDna Analysis +16