Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans

Shiny Titus, Fang Li, Robert Stobezki, +8

Science Translational Medicine

OocyteChromatinGenome InstabilityCentral RoleDna Damage +13

Ovarian Aging in Women With BRCA Germline Mutations

Wayne Lin, Shiny Titus, Fred Moy, +2

The Journal of Clinical Endocrinology & Metabolism

Profiling of E‐cadherin, β‐catenin and Ca²⁺ in embryo–uterine interactions at implantation

Rajesh Kumar Jha, Shiny Titus, Deeksha Saxena, +2

FEBS Letters

Individual-oocyte transcriptomic analysis shows that genotoxic chemotherapy depletes human primordial follicle reserve in vivo by triggering proapoptotic pathways without growth activation

Shiny Titus, Katarzyna Szymanska, B. Musul, +5

Scientific Reports

Increased chemotherapy-induced ovarian reserve loss in women with germline BRCA mutations due to oocyte deoxyribonucleic acid double strand break repair deficiency

Kutluk Oktay, Giuliano Bedoschi, Shari Goldfarb, +6

Fertility and Sterility

Genome InstabilityFemale InfertilityMedicinePathologyGynecology +5

Human embryo polarization requires PLC signaling to mediate trophectoderm specification

Meng Zhu, Marta N. Shahbazi, Ángel Martín, +18

eLife

Trophectoderm SpecificationCell LineageDevelopmental BiologySignal TransductionMedicine +12

The role of endometrial staining for CD138 as a marker of chronic endometritis in predicting live birth

Nola S. Herlihy, Amber M. Klimczak, Shiny Titus, +5

Journal of Assisted Reproduction and Genetics

InfertilityLive BirthImplantation (Embryology)Reproductive HealthGynecology +8

STAT3 and MCL-1 associate to cause a mesenchymal epithelial transition

Shiny Titus, Prashanth Narayan, Megha Murali, +2

Journal of Cell Science

Cancer BiologyTumor BiologySignaling PathwayCell RegulationImplantation (Embryology) +15

Transcriptomic landscape of granulosa cells and peripheral blood mononuclear cells in women with PCOS compared to young poor responders and women with normal response

Mauro Cozzolino, Sonia Herraiz, Shiny Titus, +6

Human Reproduction

Declining BRCA-Mediated DNA Repair in Sperm Aging and its Prevention by Sphingosine-1-Phosphate

Robert Stobezki, Shiny Titus, Dorota Halicka, +2

Reproductive Sciences

ChromatinInfertilityAndrologyGenome InstabilityBrca-mediated Dna Repair +11