Vincenzo Silani

Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

Chiara Zuccato, Andrea Ciammola, Dorotea Rigamonti et al. · Science · 2001 · 1.3K citations

Neurodegenerative Diseases, Wild-type Huntingtin Activity, Bdnf Production +12

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

Elizabeth T. Cirulli, Brittany N. Lasseigne, Slavé Petrovski et al. · Science · 2015 · 972 citations · Full text

Engineering, Exome Sequencing, Genetics +18

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

Chi-Hong Wu, Claudia Fallini, Nicola Ticozzi et al. · Nature · 2012 · 594 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Developmental Biology +8

TDP‐43 is recruited to stress granules in conditions of oxidative insult

Claudia Colombrita, Eleonora Zennaro, Claudia Fallini et al. · Journal of Neurochemistry · 2009 · 545 citations · Full text

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Zhaoming Su, Yong‐Jie Zhang, Tania F. Gendron et al. · Neuron · 2014 · 353 citations · Full text

Amyotrophic Lateral Sclerosis, Molecular Biology, Lead Small Molecules +2