David R. F. Leach

The SbcCD nuclease of <i>Escherichia coli</i> is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA

John C. Connelly, Lucy Kirkham, David R. F. Leach · Proceedings of the National Academy of Sciences · 1998 · 228 citations · Full text

DNA targeting and interference by a bacterial Argonaute nuclease

Anton Kuzmenko, Anastasiya Oguienko, Daria Esyunina et al. · Nature · 2020 · 200 citations · Full text

Natural Sciences, Oligonucleotide, Dna Replication +6

Viability of λ phages carrying a perfect palindrome in the absence of recombination nucleases

David R. F. Leach, Franklin W. Stahl · Nature · 1983 · 166 citations

λ Phages, Genetics, Phage Biology +7

The <i>sbcC</i> and <i>sbcD</i> genes of <i>Escherichia coli</i> encode a nuclease involved in palindrome inviability and genetic recombination

John C. Connelly, David R. F. Leach · Genes to Cells · 1996 · 143 citations

SbcCD Causes a Double-Strand Break at a DNA Palindrome in the Escherichia coli Chromosome

John K. Eykelenboom, John K. Blackwood, Ewa Okely et al. · Molecular Cell · 2008 · 124 citations · Full text

Genome Instability, Dna Palindrome, Double-strand Break +9