Concepedia

Defen Lu

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Publications

18

Citations

1.2K

H-Index

16

Active since

2009

Affiliations

Shandong University(Current)

State Key Laboratory of Microbial Technology

The University of Texas Southwestern Medical Center

Tsinghua University

Chinese Academy of Sciences

Defen Lu is an author at Shandong University specializing in life sciences, molecular biology, and structural biology.

ORCID

Publications per year

2009–2024

18

Publications

18

Crystal structures of STING protein reveal basis for recognition of cyclic di-GMP

Guijun Shang, Deyu Zhu, Ning Li et al. · Nature Structural & Molecular Biology · 2012 · 229 citations

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Activation of STING by targeting a pocket in the transmembrane domain

Defen Lu, Guijun Shang, Jie Li et al. · Nature · 2022 · 181 citations · Full text

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Characterization of Nuclear Localization Signal in the N Terminus of CUL4B and Its Essential Role in Cyclin E Degradation and Cell Cycle Progression

Yongxin Zou, Jun Mi, Jinpeng Cui et al. · Journal of Biological Chemistry · 2009 · 122 citations · Full text

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A conserved ion channel function of STING mediates noncanonical autophagy and cell death

Jinrui Xun, Zhichao Zhang, Bo Lv et al. · EMBO Reports · 2024 · 100 citations · Full text

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The mechanism of STING autoinhibition and activation

Sheng Liu, Bo Yang, Yingxiang Hou et al. · Molecular Cell · 2023 · 87 citations · Full text

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