Christopher D. Heinen

Recommendations for application of the functional evidence PS3/BS3 criterion using the ACMG/AMP sequence variant interpretation framework

Sarah E. Brnich, Ahmad Abou Tayoun, Fergus J. Couch et al. · Genome Medicine · 2019 · 571 citations · Full text

Mutations in <i>BRAF</i> and <i>KRAS</i> Differentially Distinguish Serrated versus Non-Serrated Hyperplastic Aberrant Crypt Foci in Humans

Daniel W. Rosenberg, Shi Yang, Devon Pleau et al. · Cancer Research · 2007 · 172 citations

Recommendations for application of the functional evidence PS3/BS3 criterion using the ACMG/AMP sequence variant interpretation framework

Sarah E. Brnich, Ahmad Abou Tayoun, Fergus J. Couch et al. · 2019 · 96 citations · Full text

Genetic Testing, Engineering, Genetics +21

Microsatellite instability in aberrant crypt foci from human colons.

Christopher D. Heinen, Narayan Shivapurkar, Zhiyu Tang et al. · PubMed · 1996 · 91 citations

Genome Instability, Engineering, Somatic Variant +12

The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway

Christopher D. Heinen, Kathleen H. Goss, James Cornelius et al. · Gastroenterology · 2002 · 69 citations

Tumor Biology, Cell Regulation, Medicine +8