Christopher D. Heinen

Recommendations for application of the functional evidence PS3/BS3 criterion using the ACMG/AMP sequence variant interpretation framework

Sarah E. Brnich, Ahmad Abou Tayoun, Fergus J. Couch et al. · Genome Medicine · 2019 · 621 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

Bryony A. Thompson, Amanda B. Spurdle, John‐Paul Plazzer et al. · Nature Genetics · 2013 · 476 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Mutations in <i>BRAF</i> and <i>KRAS</i> Differentially Distinguish Serrated versus Non-Serrated Hyperplastic Aberrant Crypt Foci in Humans

Daniel W. Rosenberg, Shi Yang, Devon Pleau et al. · Cancer Research · 2007 · 172 citations

Medicine, Oncology, Pathology +17

Recommendations for application of the functional evidence PS3/BS3 criterion using the ACMG/AMP sequence variant interpretation framework

Sarah E. Brnich, Ahmad Abou Tayoun, Fergus J. Couch et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 96 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Microsatellite instability in aberrant crypt foci from human colons.

Christopher D. Heinen, Narayan Shivapurkar, Zhiyu Tang et al. · PubMed · 1996 · 91 citations

Medicine, Genetics, Oncology +12