Editing DNA Methylation in the Mammalian Genome

X. Shawn Liu, Hao Wu, Ji Xiong, +7

Cell

ChromatinEpigenetic ChangeGeneticsDna MethylationEpigenomics +4

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

Thorold W. Theunissen, Benjamin E. Powell, Haoyi Wang, +18

Cell stem cell

FertilityAdult Stem CellKinase InhibitorsEpigeneticsNaive Human Pluripotency +14

Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression

Frank Soldner, Yonatan Stelzer, Chikdu Shivalila, +7

Nature

Neurodegenerative DiseasesMolecular NeuroscienceSynaptic SignalingGeneticsParkinson-associated Risk Variant +5

Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis

Alejandro Aguilera-Castrejon, Bernardo Oldak, Tom Shani, +23

Nature

Developmental BiologyMorphogenesisOrgan DevelopmentEmbryonic DevelopmentReproductive Biology +3

A single-embryo, single-cell time-resolved model for mouse gastrulation

Markus Mittnenzweig, Yoav Mayshar, Saifeng Cheng, +12

Cell

EmbryologyCell LineageDevelopmental BiologyMorphogenesisEmbryonic Development +3

Clone- and Gene-Specific Aberrations of Parental Imprinting in Human Induced Pluripotent Stem Cells

Marjorie Pick, Yonatan Stelzer, Ori Bar‐Nur, +3

Stem Cells

The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome

Yonatan Stelzer, Ido Sagi, Ofra Yanuka, +2

Nature Genetics

Developmental BiologyMedicineGeneticsPrader-willi SyndromeGene Regulation +8

Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution

Yonatan Stelzer, Chikdu Shivalila, Frank Soldner, +2

Cell

ChromatinEpigenetic ChangeDna MethylationDna AnalysisEpigenomics +4

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

Thorold W. Theunissen, Benjamin E. Powell, Haoyi Wang, +18

Cell stem cell

FertilityChemical BiologyPharmaceutical ChemistryTranslational PharmacologyMolecular Pharmacology +22

Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution

David Dierks, Miguel Angel García-Campos, Anna Uzonyi, +10

Nature Methods

EngineeringMedicineGeneticsComputational BiologyBiostatistics +8