Vrajesh Karkhanis

Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation

Lapo Alinari, Kiran V. Mahasenan, Fengting Yan et al. · Blood · 2015 · 143 citations · Full text

Protein Arginine Methyltransferase 7 Regulates Cellular Response to DNA Damage by Methylating Promoter Histones H2A and H4 of the Polymerase δ Catalytic Subunit Gene, POLD1

Vrajesh Karkhanis, Li Wang, Sookil Tae et al. · Journal of Biological Chemistry · 2012 · 125 citations · Full text

Histone Modifications, Dna Damage, Epigenetic Change +17

PRMT5–PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells

Yeshavanth Banasavadi‐Siddegowda, Luke Russell, E. Frair et al. · Oncogene · 2016 · 124 citations · Full text

Neuro-oncology, Molecular Neuroscience, Primary Glioblastoma +10

Protein Arginine Methyltransferase 5 (PRMT5) Inhibition Induces Lymphoma Cell Death through Reactivation of the Retinoblastoma Tumor Suppressor Pathway and Polycomb Repressor Complex 2 (PRC2) Silencing

Ji-Hyun Chung, Vrajesh Karkhanis, Sookil Tae et al. · Journal of Biological Chemistry · 2013 · 89 citations · Full text

Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes

Sookil Tae, Vrajesh Karkhanis, Kevin Velasco et al. · Nucleic Acids Research · 2011 · 87 citations · Full text