Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

Luke Whiley, Arundhuti Sen, James Heaton, +12

Neurobiology of Aging

Alzheimer's DiseaseDementiaNeurochemical BiomarkersNeurologyNeuroscience +4

Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

Petroula Proitsi, Min Kim, Luke Whiley, +13

Alzheimer s & Dementia

Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection

Torben Kimhofer, Samantha Lodge, Luke Whiley, +13

Journal of Proteome Research

Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor

George Zhang Wei, Katherine A. Martin, Peter Yuli Xing, +13

Proceedings of the National Academy of Sciences

Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer’s disease

Petroula Proitsi, M Kim, Luke Whiley, +11

Translational Psychiatry

XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules

Xavier Domingo-Almenara, J. Rafael Montenegro-Burke, Julijana Ivanišević, +14

Nature Methods

Targeted LibraryMolecular RecognitionTargeted AnalysisMolecular CharacterizationBiochemistry +11

Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome

Elaine Holmes, Julien Wist, Reika Masuda, +24

Journal of Proteome Research

Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease

Luke Whiley, Katie Chappell, Ellie D’Hondt, +13

Alzheimer s Research & Therapy

In-Vial Dual Extraction for Direct LC-MS Analysis of Plasma for Comprehensive and Highly Reproducible Metabolic Fingerprinting.

Luke Whiley, Joanna Godzień, Francisco J. Rupérez, +2

Analytical Chemistry

Lipid AnalysisEngineeringBiological Mass SpectrometryMetabolomic ProfilingIn-vial Dual Extraction +20

Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses

Nathan G. Lawler, Nicola Gray, Torben Kimhofer, +16

Journal of Proteome Research