Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

Wei Liu, Eugene Chun, Aaron A. Thompson, +9

Science

Molecular PharmacologyProteinlipid InteractionMolecular PhysiologyBiochemistryAllosteric Regulation +12

Structure of an Agonist-Bound Human A _2A Adenosine Receptor

Fei Xu, Huixian Wu, Vsevolod Katritch, +5

Science

Crystal StructureProtein AssemblyMolecular BiologyMolecular PharmacologyProtein Folding +15

Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors

Eugene Chun, Aaron A. Thompson, Wei Liu, +8

Structure

BiochemistryProtein AssemblyProtein FoldingNatural SciencesG Protein-coupled Receptor +7

Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans

Xiangyang Chen, Fei Xu, Chengming Zhu, +4

Scientific Reports

Structural basis of ligand recognition and self-activation of orphan GPR52

Xi Lin, Mingyue Li, Niandong Wang, +13

Nature

BiochemistryG Protein-coupled ReceptorMedicineNatural SciencesOrphan Gpr52 +6

Structural Basis for Apelin Control of the Human Apelin Receptor

Yingli Ma, Yang Yue, Yanbin Ma, +17

Structure

Molecular PhysiologySignal TransductionG Protein-coupled ReceptorMedicineReceptor Tyrosine Kinase +7

Crystal structure of the Frizzled 4 receptor in a ligand-free state

Shifan Yang, Yiran Wu, Ting-Hai Xu, +22

Nature

Crystal StructureEngineeringMedicineLigand-free StateMolecular Biology +7

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand

Xianjun Zhang, Fei Zhao, Yiran Wu, +18

Nature Communications

A Cytoplasmic Argonaute Protein Promotes the Inheritance of RNAi

Fei Xu, Xuezhu Feng, Xiangyang Chen, +5

Cell Reports

Core Structure of the Yeast Spt4-Spt5 Complex: A Conserved Module for Regulation of Transcription Elongation

Min Guo, Fei Xu, Jena Yamada, +5

Structure

Transcriptional RegulationCore StructureNatural SciencesGeneticsMolecular Biology +8