Allan Joaquim Lamontanara

c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease

Anne-Laure Mahul-Mellier, Bruno Fauvet, Amanda M. Gysbers et al. · Human Molecular Genetics · 2014 · 215 citations · Full text

Mitophagy, Synaptic Transmission, Cell Death +23

ATP Site Ligands Determine the Assembly State of the Abelson Kinase Regulatory Core via the Activation Loop Conformation

Rajesh Sonti, Ines Hertel-Hering, Allan Joaquim Lamontanara et al. · Journal of the American Chemical Society · 2018 · 64 citations · Full text

Protein Assembly, Atp Site Ligands, Molecular Biology +17

Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface

John Wojcik, Allan Joaquim Lamontanara, Grzegorz J. Grabe et al. · Journal of Biological Chemistry · 2016 · 53 citations · Full text

Src Homology 2, Signal Transduction, Allosteric Inhibition +13

The SH2 domain of Abl kinases regulates kinase autophosphorylation by controlling activation loop accessibility

Allan Joaquim Lamontanara, Sandrine Georgeon, Giancarlo Tria et al. · Nature Communications · 2014 · 52 citations · Full text

Activation Loop Accessibility, Signal Transduction, Cell Regulation +14

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms

Daniel Duarte, Allan Joaquim Lamontanara, Giuseppina La Sala et al. · Nature Communications · 2020 · 43 citations · Full text