Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer model

Xiping Xin, Mousumi Majumder, Gannareddy V. Girish, +3

Laboratory Investigation

Breast OncologyMedicineTumor GrowthCancer GrowthPathology +9

The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis

Elena Tutunea-Fatan, Mousumi Majumder, Xiping Xin, +1

Molecular Cancer

COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis

Mousumi Majumder, Xiping Xin, Ling Liu, +6

Stem Cells

Cancer BiologyTumor BiologySlc MarkersCox-2 Induces SlcsSignaling Pathway +14

Diabetes-Induced Extracellular Matrix Protein Expression Is Mediated by Transcription Coactivator p300

Harkiran Kaur, Shali Chen, Xiping Xin, +3

Diabetes

Prostaglandin E2 receptor <scp>EP</scp>4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem‐like cell functions

Mousumi Majumder, Xiping Xin, Ling Liu, +2

Cancer Science

PGE2 promotes breast cancer-associated lymphangiogenesis by activation of EP4 receptor on lymphatic endothelial cells

Pinki Nandi, Gannareddy V. Girish, Mousumi Majumder, +3

BMC Cancer

Extracellular signal-regulated kinase (ERK) in glucose-induced and endothelin-mediated fibronectin synthesis

Xiping Xin, Zia A. Khan, Shali Chen, +1

Laboratory Investigation

Cell PhysiologySignal TransductionReceptor Tyrosine KinaseDiabetesPhysiology +6

Co-Expression of α9β1 Integrin and VEGF-D Confers Lymphatic Metastatic Ability to a Human Breast Cancer Cell Line MDA-MB-468LN

Mousumi Majumder, Elena Tutunea-Fatan, Xiping Xin, +7

PLoS ONE

Glucose-induced Akt1 activation mediates fibronectin synthesis in endothelial cells

Xiping Xin, Zia A. Khan, S. Chen, +1

Diabetologia

Signal TransductionDiabetesEndothelial DysfunctionVascular BiologyGlucose-induced Akt1 Activation +5

Akt activation and augmented fibronectin production in hyperhexosemia

Xiping Xin, Shali Chen, Zia A. Khan, +1

American Journal of Physiology-Endocrinology and Metabolism

Akt ActivationGlycobiologyCellular PhysiologyInsulin SignalingEcm Protein Production +20