R. Marc Learned

Identification of a Nuclear Receptor for Bile Acids

Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa et al. · Science · 1999 · 2.7K citations

Life Sciences, Genetics, Molecular Biology +17

T0070907, a Selective Ligand for Peroxisome Proliferator-activated Receptor γ, Functions as an Antagonist of Biochemical and Cellular Activities

Gary Lee, Fabienne Elwood, John McNally et al. · Journal of Biological Chemistry · 2002 · 320 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Separating Tumorigenicity from Bile Acid Regulatory Activity for Endocrine Hormone FGF19

Mei Zhou, Xueyan Wang, Darrin A. Lindhout et al. · Cancer Research · 2014 · 178 citations

Medicine, Cancer Biology, Oncology +16

A nontumorigenic variant of FGF19 treats cholestatic liver diseases

Jian Luo, Brian Ko, M Elliott et al. · Science Translational Medicine · 2014 · 167 citations

Medicine, Molecular Medicine, Oncology +11

Selective, covalent modification of β-tubulin residue Cys-239 by T138067, an antitumor agent with <i>in vivo</i> efficacy against multidrug-resistant tumors

Bei Shan, Julio C. Medina, Edit Santha et al. · Proceedings of the National Academy of Sciences · 1999 · 163 citations · Full text

Life Sciences, Molecular Biology, Oncology +17