Daniele Donati

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

Paola Magnaghi, Roberto D’Alessio, Barbara Valsasina et al. · Nature Chemical Biology · 2013 · 380 citations

Biochemistry, Medicine, Natural Sciences +10

Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Elena Ardini, Maria Menichincheri, Patrizia Banfi et al. · Molecular Cancer Therapeutics · 2016 · 308 citations · Full text

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Maria Menichincheri, Elena Ardini, Paola Magnaghi et al. · Journal of Medicinal Chemistry · 2016 · 294 citations · Full text

Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase

Riccardo Colombo, Marina Caldarelli, Milena Mennecozzi et al. · Cancer Research · 2010 · 199 citations · Full text

Cancer Therapy, Mitotic Checkpoint, Mps1 Kinase +14

The TPM3‐NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition

Elena Ardini, Roberta Bosotti, Andrea Borgia et al. · Molecular Oncology · 2014 · 151 citations · Full text

Trka Kinase Inhibition, Pathology, Cancer Biology +21