Christopher J. Staples

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the <i>DUSP6</i>/<i>MKP</i>-<i>3</i> gene promoter

Maria Ekerot, Marios P. Stavridis, Laurent Delavaine et al. · Biochemical Journal · 2008 · 185 citations · Full text

Molecular Regulation, Negative-feedback Regulation, Transcriptional Regulation +18

Regulation of the inducible nuclear dual-specificity phosphatase DUSP5 by ERK MAPK

Anna Kucharská, Linda Rushworth, Christopher J. Staples et al. · Cellular Signalling · 2009 · 111 citations

Signal Transduction, Signaling Pathway, Cell Regulation +10

The centriolar satellite protein Cep131 is important for genome stability.

Christopher J. Staples, Katie Myers, D. D. Beveridge Ryan et al. · Journal of Cell Science · 2012 · 101 citations

Cross-talk between the p38α and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation

Christopher J. Staples, David M. Owens, Jana V. Maier et al. · Journal of Biological Chemistry · 2010 · 78 citations · Full text

Apoptosis, Cell Death, Cellular Physiology +16

CDK4/6 inhibitor-mediated cell overgrowth triggers osmotic and replication stress to promote senescence

Lisa Crozier, Reece Foy, Rozita Adib et al. · Molecular Cell · 2023 · 69 citations · Full text

Cell Proliferation, Cell Cycle, Cancer Biology +16