Concepedia

Christian M. Orr

CM

Statistics

Publications

10

Citations

469

H-Index

10

Active since

2018

Affiliations

Diamond Light Source(Current)

University of Southampton

Universität Hamburg

Imperial College London

SPring-8

Christian M. Orr is an author at Diamond Light Source specializing in biochemistry, structural biology, and life sciences.

ORCID

Publications per year

2018–2023

10

Publications

10

Reducing affinity as a strategy to boost immunomodulatory antibody agonism

Xiaojie Yu, Christian M. Orr, H.T. Claude Chan et al. · Nature · 2023 · 116 citations · Full text

, , +12

Complex Interplay between Epitope Specificity and Isotype Dictates the Biological Activity of Anti-human CD40 Antibodies

Xiaojie Yu, H.T. Claude Chan, Christian M. Orr et al. · Cancer Cell · 2018 · 111 citations · Full text

, , +17

Hinge disulfides in human IgG2 CD40 antibodies modulate receptor signaling by regulation of conformation and flexibility

Christian M. Orr, Hayden Fisher, Xiaojie Yu et al. · Science Immunology · 2022 · 49 citations

, , +17

Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1

Elyse S. Fischer, C. Yu, Dom Bellini et al. · EMBO Reports · 2021 · 43 citations · Full text

, , +14

Serial Femtosecond Crystallography Reveals that Photoactivation in a Fluorescent Protein Proceeds via the Hula Twist Mechanism

Alisia Fadini, C. Hutchison, Dmitry Morozov et al. · Journal of the American Chemical Society · 2023 · 29 citations · Full text

, , +16

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