Ivo Frydrych

Caffeine–hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells

Robert Kaplánek, Milan Jakubek, Jakub Rak et al. · Bioorganic Chemistry · 2015 · 51 citations

Tumor Biology, Medicine, Cancer Cell Biology +10

Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid

Lucie Borková, Ivo Frydrych, Nikola Jakubcová et al. · European Journal of Medicinal Chemistry · 2019 · 47 citations

Betulonic Acid, Triterpenoid Thiazoles, Ursonic Acid +3

A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA

Alicia Wong, Danuta Bryzek, Ewelina Dobosz et al. · The Journal of Immunology · 2018 · 38 citations · Full text

Citrullinated Residues, Immunology, Molecular Biology +19

Serine protease inhibitors <i>N</i>‐α‐Tosyl‐<scp>L</scp>‐Lysinyl‐Chloromethylketone (TLCK) and <i>N</i>‐Tosyl‐<scp>L</scp>‐Phenylalaninyl‐Chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases

Ivo Frydrych, Petr Mlejnek · Journal of Cellular Biochemistry · 2007 · 31 citations · Full text

Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells

Lucie Borková, Lucie Jašíková, Katerina Frisonsova et al. · European Journal of Medicinal Chemistry · 2015 · 30 citations

Cytotoxic 2,2-Difluoroderivatives, Dihydrobetulinic Acid, Bioorganic Chemistry +6